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PMC 4466421

Yet doctors claim they pose significant health risks to users that are frighteningly similar to those of conventional cigarettes

It is important to understand the histology of the oral mucosa because some lesions (e.g., minor aphthous ulcers) tend to involve primarily the nonkeratinized tissues: buccal mucosa, labial mucosa (wet surface of the lip), maxillary and mandibular sulcus or vestibule (the gully between the jawbones and the buccal or labial mucosa), nonattached gingiva, ventral tongue, floor of mouth, and soft palate