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Plays a Function in Maintaining Heart Health Vitamin B12 benefits cardiovascular health in numerous ways, which is very important considering that heart disease is currently the primary cause of fatality worldwide

The cardiovascular outcomes data are not expected to be available in time for an initial NDA filing, which is consistent with regulatory precedent: the FDA can approve an obesity agent based on weight and safety data, then require post-marketing cardiovascular outcome data as a condition of approval

When used for weight management, the evidence increasingly supports long-term or indefinite treatment for patients who respond well and tolerate the medication particularly those with obesity-related cardiovascular risk factors

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