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In contrast to the previously mentioned study, opening of L-type Ca 2+ channels was not essential for peptone-mediated GLP-1 secretion, because nifedipine only blocked GLP-1 secretion following the luminal perfusion of glucose and not peptones (127)

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However, we observed similar improvements with combined exercise and liraglutide treatment as with exercise alone, but liraglutide treatment alone had no effect

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