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Long-term use of proton pump inhibitors and metformin can impair B12 absorption, necessitating monitoring or parenteral therapy

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Administration in the documented research protocol is subcutaneous , using a small-gauge U-100 insulin syringe

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Report any suspected side effects to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk

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Per week: 14 swabs (2/day) 8 weeks: 112 swabs recommend 2 100-count boxes 12 weeks: 168 swabs recommend 2 100-count boxes 16 weeks: 224 swabs recommend 3 100-count boxes Protocol Overview Concise summary of the once-daily regimen

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