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It: Stimulates insulin secretion (only when glucose is elevated) Suppresses glucagon Slows gastric emptying Reduces appetite Promotes satiety Due to these effects, GLP-1 plays a central role in blood glucose regulation, weight management, and metabolic health

Brushing your teeth immediately before or after dosing is another mistake

(1) GLP-1 receptors are present in other organs including pancreas, heart, brain, lungs, adipose, kidneys, GI tract, adrenal glands, spleen, and eyes

The steady-state 24-hour urinary glucose excretion in patients with type 2 diabetes mellitus and mild, moderate, and severe renal impairment was 42%, 80%, and 90% lower, respectively, than in patients with type 2 diabetes mellitus with normal renal function