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These cases often involve an interplay between neuroautoimmunity and immune hypersensitivity, with mast cells amplifying the inflammatory response to microbial triggers

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During the recruitment appointment and subsequent follow-up appointments at six and twelve months, the clinical status and mental health of all volunteers were evaluated, peripheral blood samples were collected, 45 plasma biomarkers (cytokines, chemokines, and growth factors) were assessed, and a comprehensive investigation was conducted using neuropsychological and ophthalmological tests, PET-CT, and magnetic resonance neuroimaging