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Given the widespread use of ondansetron in pregnancy, data establishing product efficacy and methodologically rigorous evaluation of post-marketing safety are needed. Research on Birth Defects: What Studies Show Studies have given conflicting results about the potential for Zofran to cause birth defects

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Researchers are investigating genetic variants in GLP-1 receptor pathways, gut microbiome profiles, and baseline hormone levels to determine who will respond best to GLP-1 therapy, who might benefit from dual agonists, and who is more prone to side effects

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