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3 Chemical metabolites SCF contains a variety of bioactive metabolites, such as lignans ( SCF contains a diverse array of bioactive metabolites spanning multiple chemical classes (see Table 1), which catalogs 18 representative compounds including biphenyl cyclooctene lignans, triterpenoids, and cyclohexane derivatives, with their respective molecular formulas, molecular weights, and bibliographic references. Among the 18 chemical metabolites listed in Table 1, the biphenyl cyclooctene lignans represent the most extensively studied class of bioactive compounds in the context of MASLD

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