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10.1038/nrn3407 [DOI] [PMC free article] [PubMed] [Google Scholar] Xiong Z

While gabapentin can significantly reduce nerve-related sciatica symptoms, it requires patience for gradual dose escalation and works best combined with physical therapy rather than as monotherapy

"In addiction medicine, a lot of treatments target just one thing, for example, a nicotine patch helps with smoking, but not alcohol, but there is no medication that works across addictive substances, let alone all of them," said senior author Ziyad Al-Aly, MD, a WashU Medicine clinical epidemiologist and Chief of the Research and Development Service at the VA Saint Louis Health Care System