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Treatment of hypertension during pregnancy as a replacement for ACE inhibitors & ARBs The patient can be switched back to an ACE inhibitor or ARB once pregnancy is over Notes: Methyldopa is the L-isomer of alpha-methyldopa References: Benowitz NL (2024): Antihypertensive Agents (Chapter 11)

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The different intermediates provide precursors for some amino acids as well as nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2), which enter the electron transport chain (ETC) that is located within the inner mitochondrial membrane