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doi: 10.1016/j.psyneuen.2013.06.026 208 TaoRde ZoetenEFOzkaynakEChenCWangLPorrettPMet al

20 Additionally, various dipeptidyl peptidase IV inhibitors have been utilized, such as sitagliptin, which was found not to improve liver enzymes, liver fat content or liver fibrosis in patients with NAFLD

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Among the main inflammatory mediators, CRP plays a crucial role in atherogenesis by promoting complement activation, enhancing macrophage lipid uptake, stimulating pro-inflammatory cytokine release, inducing monocyte tissue factor expression, impairing endothelial function, and inhibiting nitric oxide production, further aggravating vascular injury (Shrivastava et al