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Discussion The metabolic importance of vitamin B 12 and folate stems principally from their central role in one carbon metabolism, 2 where they are essential for the functioning of several coenzymes

Ingredients 1 mg cyanocobalamin, water for injections, sodium hydroxide for pH adjustment, sodium chloride, sodium dihydrogen phosphate 2 water Directions At the beginning of the treatment, 1 ampoule of 1 ml vitamin B 12 Lichtenstein (corresponding to 1000 micrograms of cyanocobalamin) is administered twice a week in the first weeks after diagnosis