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The OAT revealed intestinal fungal overgrowth and a significant need for methylation support due to toxic exposure

A 2026 ex-vivo study in human internal mammary artery tissue (Yildirim et al., J Clin Med 15(9):3488, PMID 42123221) provided the first human-tissue mechanism evidence for BPC-157s endothelium-dependent, nitric-oxide-mediated vasorelaxation anchoring the previously preclinical NO-pathway literature in human ex-vivo data

doi: 10.1016/j.jdermsci.2019.02.004