is semaglutide in short supply shortage ends as FDA sets deadline for compounders FDA declares end to Wegovy

Effects of GLP-1 on Blood Sugar and Insulin Sensitivity GLP-1 receptor agonists exert significant beneficial effects on glucose metabolism and insulin sensitivity, which are central to their therapeutic value

We had assumed it was a consequence of losing weight but this seems to suggest theres a separate pathway. We dont know how those effects would play out in patients at a healthy weight, because they werent part of the study so it doesnt mean that semaglutides should be considered as a treatment for anyone with heart issues regardless of their weight

The blood pressure reductions observed in trials are likely multi-factorial and predominantly weight-loss mediated

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