fda glp-1 compounding crackdown news october 2025 Intensifies on Compounded weight-loss and hormone drugs

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Lisa Clay, MD Board-Certified Family Physician Founder & Medical Director, Monarch Medicine Urgent Care March 2026 GLP-1 weight loss therapy at Monarch Medicine uses compounded semaglutide and tirzepatide prepared by a licensed compounding pharmacy

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We noticed that for GLP-1 there were multiple immunoreactive forms of different sizes.in our second paper we used these smaller peptides to show that GLP-1 stimulates insulin gene expression and secretion from pancreatic islets