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In animal models of heart failure induced by high-frequency pacing, ischaemia, and obesity, GLP-1RAs inhibit left ventricular remodelling and improve left ventricular contractility and diastolic function through anti-inflammatory effects, cardiomyocyte apoptosis inhibition, and glucose metabolism enhancement in cardiomyocytes [38,39,40]

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Expected Weight Loss Results Clinical trials of semaglutide 2.4 mg injections showed meaningful weight reduction

3B ) and IL-10 (all p 0.017 sex, treatment and diet interaction: F (1,40) = 4.258, p 2 = 0.155, p = 0.046