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doi: 10.1038/s42255-019-0073-4 8
Summary: Secretagogues vs HGH Decision Matrix For the majority of men over 35 with an intact pituitary who are seeking GH optimisation for body composition, recovery, and anti-ageing, secretagogues represent the better starting position on every dimension: mechanism, safety profile, cost, and legal standing
Best for: Constipation (because it functions as an osmotic laxative) Not great for: Repleting magnesium status Performance, recovery, sleep optimization Why: Magnesium oxide is poorly absorbed compared with many organic salts and chelates
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