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However, impressive outcomes in clinical trials can fail to translate into sustained real-world success

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279 The phase 3 HELIOS-B trial (NCT04153149), a multicenter, double-blind, randomized controlled trial, recently reported that vutrisiran reduced the primary endpoint, a composite of all-cause mortality and recurrent cardiovascular events, by 28% in the overall population and by 33% in the monotherapy subgroup

And we recognize that the insights gained from self-funded research may not have come to light had the manufacturer not invested its resources, and we also appreciate that Pendulum is consistently willing to invest such resources, as there are even more clinical trials upcoming on the companys docket