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The importance of 3-AR was verified when long-term treatment with AOD9604 in 3-AR knockout mice failed to produce the changes in body weight and increase in lipolysis observed in wild-type control mice

The two groups adhered to the same rehabilitation regimen, and their respective medication regimens did not differ significantly

Individual side effects (nausea, injection-site reactions) can occur with either agent alone, but combined use raises localized inflammation risk from frequent injections