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The FDA has raised concerns about purity, immune reactions and the lack of human research

Unlike established compounds with decades of clinical data, optimal dosing remains uncertain

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According to this evidence, platelet hyper-reactivity certainly concurs to the development of life-threatening thrombotic complications in T2D patients, with current antiplatelet agents proven to be less effective in diabetic patients, with a high percentage of low or non-responders (Rivas Rios et al., 2018)