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To obtain more detailed information on accurate regulation of the release profile of insulin-loaded particles, three kinds of uniform-sized insulin microspheres were prepared using the solvent extraction, solvent evaporation and cosolvent methods, respectively [46]

10.1016/j.jcf.2021.01.010 J Cyst Fibros

Researchers became interested in combining these peptides when early studies revealed their complementary pharmacokinetics: Ipamorelin peptide provides an immediate GH pulse (peaking within 40 minutes), while CJC-1295 sustains release over several hours