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They may also offer cardiovascular and metabolic benefits

The unabsorbed residues deposit in the intestine, which forces the intestinal mucosa to fill with large quantities of black or brown pigment.31 The use of anthraquinone laxatives can result in the displacement of electrolytes and water loss in the intestinal tract and sequentially lead to the deposition of protein products after using such laxatives for a long period

Encouraging Long-Term Perspective While early results can be encouraging, patients should understand that these therapies are part of a long-term strategy

Ranganath ( In the central nervous system, proglucagon and proglucagon-derived peptides (GLP-1, glucagon-like peptide-2, GLP-2, and oxyntomodulin, OXM) are only present in a small group of neurons in the nucleus tractus solitarius (27)