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It refers to a noticeable change in facial appearance, often characterized by sagging or changes in facial volume, which some individuals experience after significant weight loss while using semaglutide

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Sample inclusion/exclusion, cell and region selection, image acquisition, measurement, and data entry Any sample partially destroyed by unexpected operational errors (for example, immunostaining slides exposed to strong mercury lamp light, ovaries with overdrying, frozen blot samples falling into a warm water bath, immunostaining and immunohistochemistry cell and tissue samples disrupted by accidental coverslip displacement) will be excluded