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: 15-20%

6.1 -Cell damage by ROS Pancreatic -cells exhibit a unique vulnerability to OS due to their inherently low expression of antioxidant enzymes (SOD, CAT, and GPx) and their high metabolic activity, which generates substantial ROS under hyperglycemic conditions ( cells have been proposed, among which are hyperglycemia, hyperlipidemia, hypoxia, and endoplasmic reticulum (ER)

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10.1002/mco2.520 193 YangZ.JiangY.XiaoY.QianL.JiangY.HuY.et al (2024c)