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In a CPR-induced I/R pig model, the aldehyde dehydrogenase 2 (ALDH2) activator ALDA-1 alleviated renal injury: compared to the CPR group, ALDA-1 treatment reduced renal iron deposition, MDA, 4-HNE, and ACSL4 levels, while increasing GSH and GPX4 expression (89)

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[7] The US Food and Drug Administration (FDA) approved dulaglutide with a Risk Evaluation and Mitigation Strategy (REMS), [7] and granted the approval of Trulicity to Eli Lilly and Company