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Given its safety profile and broad range of beneficial effects (antioxidant, anti-inflammatory, anti-aggregation, and neurogenic), curcumin stands out as a promising adjunctive treatment for PD

This led to the assumption that the primary receptors mediating weight loss for this target class were AMYRs, yet, dual agonists are reported to have higher efficacy than AMYR selective agonists 2,10,11,12

This includes people who are pregnant, have cardiovascular conditions, experience heat sensitivity or have low blood pressure

Recent studies suggest that gut dysbiosis, a driver of inflammation and mineral imbalance, warrants exploration as a novel therapeutic avenue, potentially through microbiome-targeted interventions (125)